Femara (Letrozole Tablets) : Buy Online Canada Drugs at Discount PriceManufactured by: Novartis |
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Femara (letrozole) is an aromatase inhibitor used to treat breast cancer in women after menopause.
FEMARA (letrozole tablets) is an aromatase inhibitor used for the treatment of postmenopausal women with hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic breast cancer. Femara (letrozole) is also indicated for the treatment of advanced cancer in postmenopausal women with disease progression following antiestrogen therapy. In choosing Femara (letrozole), your doctor has considered many factors. They include your age, the characteristics of your cancer, and whether you are premenopausal (still having menstrual periods) or postmenopausal (no longer having menstrual periods).
Typically there are two situations in which Femara (letrozole) is used. Femara (letrozole) may be prescribed as a woman's first hormonal therapy, or Femara (letrozole) may be prescribed after she has received previous therapy with tamoxifen or another antiestrogen, and her cancer is no longer controlled by that therapy. Femara (letrozole) should not be used in women who are premenopausal. Femara (letrozole) may cause fetal harm if given to pregnant women.
To understand how this class of drugs works, it is necessary to have some basic understanding of the way estrogen affects certain breast cancer cells. Hormone-dependent breast cancers contain protein molecules called estrogen receptors. When no estrogen is present, the estrogen receptors remain inactive. When the estrogen receptors are exposed to estrogen, however, they trigger a chain of events that results in tumor cell growth and multiplication. Tumors that contain these estrogen receptors are known as estrogen receptor-positive (ER+) tumors. These are the cancers that can be treated by Femara (letrozole) (and other hormonal therapies), to deprive them of estrogen. Your doctor may have performed a test to determine whether your tumor is estrogen receptor-positive or estrogen receptor-negative (ER-). Estrogen receptor-negative tumors grow without stimulation from estrogen; hormonal therapies are less effective in treating these cancers.
By interfering with the production of estrogen triggered by aromatase, aromatase inhibitors actually reduce the total amount of estrogen in the body. As a result, less estrogen can reach breast cancer cells. Thus, these drugs help to starve breast cancer cells in postmenopausal women by depriving them of estrogen. The next illustration shows the effect of estrogen deprivation on the multiplication of breast cancer cells.
FEMARA (letrozole tablets) is a highly potent estrogen suppressor in postmenopausal women with advanced breast cancer.
Androgen (a hormone found in both men and women) is produced by fat, muscle, and adrenal glands. Aromatase enzyme is needed to convert androgen into estrogen, which results in tumor growth. Femara (letrozole) binds to the aromatase enzyme and blocks it from converting androgen to estrogen, thereby reducing growth of the tumor.
Femara (letrozole) is a convenient therapy. You take just one 2.5-mg tablet once each day. Taking Femara (letrozole) at the same time each day will help you remember to take your therapy. If you forget to take your dose at your regular time, take it as soon as you remember. However, you should not take more than one pill each day. Food does not affect the absorption or the effectiveness of Femara (letrozole), so you can take Femara (letrozole) with or without food.
It is important to let your doctor know about all other drugs you are taking, even the over-the-counter (nonprescription) medications. Your doctor will best be able to determine which medications you may not take with Femara (letrozole). Your doctor will want you to keep taking Femara (letrozole) as long as you continue to benefit from it.
There are various ways in which your doctor can measure your response to Femara (letrozole) therapy; these may include physical examination, x-ray, bone scan, and CAT scan (Computerized Axial Tomography). FEMARA (letrozole tablets) is not chemotherapy. Femara (letrozole) is a form of hormonal therapy, and, as such, it acts differently than chemotherapy. In a clinical study, few patients (5%) who received 2.5 mg of Femara (letrozole) daily had hair thinning.
At the recommended daily dose of 2.5 mg, Femara (letrozole) is generally well tolerated. Most of the side effects that were observed in women who received Femara (letrozole) in clinical studies were not considered serious and were generally mild to moderate. Most common side effects included bone pain, hot flushes, back pain, dyspnea, nausea, arthralgia, coughing, fatigue, constipation, pain in the limb, chest pain, and headache.
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Femara belongs to a class of medications called an oral, anti-estrogen drug, commonly used for relief and treatment for postmenopausal women with breast cancer. Generally Femara/Letrozole acts by preventing the action of an enzyme in the body called the aromatase enzyme. Femara comes in category of drugs called also Letrozole. Femara/Letrozole is being manufactured by Novartis Pharmaceuticals and is available in 2.5mg Tablets. What are the most common problems for which Femara/Letrozole is used? Femara/Letrozole is useful for the treatment of postmenopausal women with hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic breast cancer. The breast is a gland that surrounded by fat and a group of breast tissues that supported by flesh, which is a connective tissue. Breast cancer develops from the cells, Cancer cells that remain restricted to the lobule and the ducts are called 'non-invasive'. Femara/Letrozole is more useful medicine for the treatment of advanced cancer in postmenopausal women with disease progression following antiestrogen therapy. Femara/Letrozole is useful for Pre-operative treatment of localized breast cancer in postmenopausal women, to allow breast-conserving surgery. Femara/Letrozole may also be used for relieve other conditions that determined by your doctor or consultant. How does Femara/Letrozole work? Femara/Letrozole belongs to a class of medications called an oral, anti-estrogen drug, commonly used for relief and treatment for postmenopausal women with breast cancer. Femara/Letrozole is an aromatase inhibitor; it works in an entirely different way than some other hormonal therapies. Femara/Letrozole works by preventing the action of an enzyme in the body called the aromatase enzyme. The aromatase enzyme is normally involved in the production of the female sex hormone, oestrogen. Femara/Letrozole actually reduces the total amount of estrogen in the body, thereby limiting the amount of estrogen that can reach the cancer cells. The aromatase enzyme converts the androstenedione hormones produced by the ovary and testosterone, by oestrogen that’s effective for sex, in post-menopausal women. Generally breast cancers are sensitive to oestrogen, and their growth is varied in the availability of this hormone. Therefore lowering the levels of oestrogen in the body Femara/Letrozole is useful in the treatment of oestrogen sensitive breast cancer. Is any prescription required to get Femara/Letrozole? Yes, prescription is necessary, one most not to use Femara/Letrozole without prescription. Some times in such conditions Femara/Letrozole is more harmful for health so, it is better to use Femara/Letrozole under doctor’s guidance or according to your medical consultant. Femara/Letrozole Tablets always take under doctor’s guidance. The recommended starting dosages of Femara/Letrozole Tablets will be different for different patients and taken once daily or as directed by doctor. You continue to take it for as long as your doctor prescribes it. Anybody should take the recommended oral dosage of Femara/Letrozole Tablets is taking with meals and a full glass of water. What is the minimum duration for which Femara/Letrozole should be taken? The duration of taking Femara/Letrozole is not constant; it depends according to the problem. Your doctor or consultant can describe you better about the time period for which duration Femara/Letrozole should be taken or until the medication is deemed effective. Your dose may need to be gradually decreased by your doctor. Are there any side effects of Femara/Letrozole? Possible side effects that occur during the uses of Femara/Letrozole:
Under what circumstances Femara/Letrozole should not be used? If you have an allergy to Femara/Letrozole Tablets or any other ingredients of this medicine, then should not be used. Femara/Letrozole is unsafe for Pre-menopausal women, anybody should not be used without consultion of doctor. If you have suffering to decreased liver problem, Femara/Letrozole should not be used without consulting of doctor. If you have suffering to the problem of high blood pressure, Femara/Letrozole should not be used without consulting of doctor. If you have suffering to the problem of kidney disease, Femara/Letrozole should not be used without consulting of doctor. If you have suffering to pregnancy or plan to be pregnant, Femara/Letrozole should not be used without consulting of doctor. If you have suffering to breastfeeding, Femara/Letrozole should not be used without consulting of doctor. Under which storage conditions Femara/Letrozole should be kept? Femara/Letrozole should be stored in cupboard at room temperature, away from heat, moisture, and direct light. Do not store Femara/Letrozole Tablets in the bathroom, near the kitchen sink, or in other damp places. Keep always Femara/Letrozole medicine out of the reach of children.
Similar drugs Femara/Letrozole
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